Antonsen has cooperated with such comedians as Harald Eia, Bård Tufte Johansen, Espen Thoresen Hværsaagod-Takkskalduha, Kristopher Schau and Johan Golden. Atle Antonsen and Johan Golden currently host a weekly radio show called "Misjonen" ("The Mission") on Fridays on Norwegian national radio station P4. The show first aired in August 2008, and was a continuation of their previous radio show "Kommisjonen" ("The Commission") which aired on now-defunct radio station Kanal 24.
Sings in a rock band called DDR, most famous for their comical music videos with "sleazy styled East Germans", also with Johan Golden.
On 1 September 2007, at the Norwegian Comedy Awards, Antonsen was awarded the Male Comedian of the Year. He started his speech by saying that the last time he won an award, his mother told him that he didn't thank people properly, and that he was going to do better this time. He paused for a couple of seconds before shouting out "Damnit! (Faen!) Didn't work this time either."
In 2012 he starred as King Arthur in the highly successful Norwegian staging of Spamalot, at Folketeatret in Oslo.