Career in music
In 1946, he became the booker & then the director of the country music radio program "Hayloft Jamboree" on WCOP (now WWDJ) in Boston, Massachucetts. In the early 1960s he began working at Pickwick Records in New York City. At Pickwick, he produced one of the first memorial recordings of President John F. Kennedy after the President's death in 1963. He left Pickwick to start his own record label, Little Darlin', in 1966. The most successful Little Darlin' records were done by the country & western singer and songwriter Johnny Paycheck. Mayhew co-wrote some of Paycheck's songs. At the end of the 1960s, he suspended the Little Darlin' label & launched a new label, Certron. The best known Certron release is the 1970 single "Burning Bridges" by Clint Eastwood.
Collector of Kennedy memorabilia
In 1966, his book "The World's Tribute to John F. Kennedy in Medallic Art" was published by William Morrow and Company. In 1970 he became widely known outside of the music business, and as a Kennedy collector, when he purchased at auction the infamous 7-story warehouse building that had housed the Texas School Book Depository in Dallas, Texas.
He has three sons, Lawrence, Michael, & Parris, & a daughter, Casey.