The northern part of the neighborhood was developed by Harold W. Miller in the 1940s, taking advantage of the popularity of nearby Audubon Park, by subdividing the land into small lots and building inexpensive homes. Audubon Park unsuccessfully tried to block creation of the neighborhood. The southern part of the neighborhood became the site of John J. Audubon Elementary School with the remainder being developed as the Glenafton subdivision in the mid-1960s.
In the 2000 census, Audubon had a population of 3,293; of which 96.5% are white, 1.7% are listed as other, 1.6% are black, and 0.2% are Hispanic. College graduates are 31.2% of the population, people without a high school degree are 15.5%. Females outnumber males 52.9% to 47.1%.