Awa-Kamogawa Station is served by the Sotobō Line and Uchibō Line, and forms the terminating point of both lines. It is located 97.3 km from the northern terminus of the Sotobō Line at Chiba Station and 119.4 km from the northern terminus of the Uchibō Line at Soga Station.
The station consists of one island platform serving two tracks for the Sotobō Line, and one side platform serving the Uchibō Line. The station shares the distinction with Kamaishi Station and Kagoshima Station of being one of only three stations in Japan serving as the terminus of two lines, with only up traffic. The station building is on the east side. There is also a west exit near to Aeon and Kamogawa City Hall connected to east one with a bridge.
Awa-Kamogawa Station opened on July 11, 1925 as a station on the Hōjō Line. The Hōjō Line was merged into the Bōsō Line in 1929, and the Bōsō Line itself was divided into the Bōsō-East and Bōsō-West Lines on April 1, 1933. These lines were renamed on July 15, 1972 to the Sotobō Line and Uchibō Line.The station was absorbed into the JR East network upon the privatization of the Japan National Railways (JNR) on April 1, 1987. A new station building was completed in August 2006.