Azelnidipine

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Azelnidipine
Azelnidipine.png
Systematic (IUPAC) name
O3-[1-[di(phenyl)methyl]azetidin-3-yl] O5-propan-2-yl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Clinical data
AHFS/Drugs.com International Drug Names
Legal status Prescription only
Routes Oral
Identifiers
CAS number 123524-52-7 N
ATC code None
PubChem CID 65948
ChemSpider 59352 YesY
UNII PV23P19YUG YesY
KEGG D01145 YesY
ChEMBL CHEMBL1275868 N
Chemical data
Formula C33H34N4O6 
Mol. mass 582.64 g/mol
 N (what is this?)  (verify)

Azelnidipine (INN; marketed under the brand name Calblock) is a dihydropyridine calcium channel blocker. It is sold in Japan by Daiichi-Sankyo pharmaceuticals, Inc. Unlike nicardipine, it has a gradual onset and has a long-lasting hypotensive effect, with little increase in heart rate.[1]

References[edit]

  1. ^ Oizumi K, Nishino H, Koike H, Sada T, Miyamoto M, Kimura T (September 1989). "Antihypertensive effects of CS-905, a novel dihydropyridine Ca++ channel blocker" ([dead link]Scholar search). Jpn. J. Pharmacol. 51 (1): 57–64. doi:10.1254/jjp.51.57. PMID 2810942.