Azurophilic granule
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| Azurophilic granule | |
|---|---|
| Latin | granulum azurophilum |
| Code | TH H2.00.04.1.02011 TH H2.00.04.1.02014 |
An azurophil is an object readily stained with an azure dye. [1] Azurophils include certain cytoplasmic granules[2] in white blood cells and hyperchromatin, imparting a burgundy or merlot coloration. Neutrophils in particular are known for containing azurophils loaded with a wide variety of anti-microbial defensins that fuse with phagocytic vacuoles. Azurophils may contain myeloperoxidase, phospholipase A2, Acid Hydrolases, Elastase, defensins, neutral serine proteases, bactericidal/permeability-increasing protein, [3] lysozyme, cathepsin G, proteinase 3, and proteoglycans.
Azurophil granules are also known as "primary granules".[4]
[edit] See also
[edit] References
- ^ azurophil at eMedicine Dictionary
- ^ "azurophil granuleazurophilic granule" at Dorland's Medical Dictionary
- ^ "Phagocytes-Neutrophils". http://www.dent.ucla.edu/pic/members/neutrophils/neutrophils2.html.
- ^ John P. Greer; Maxwell Myer Wintrobe (1 December 2008). Wintrobe's clinical hematology. Lippincott Williams & Wilkins. pp. 173–. ISBN 9780781765077. http://books.google.com/books?id=68enzUD7BVgC&pg=PA173. Retrieved 10 November 2010.
[edit] External links
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