He played for Industriales of the Cuban National Series for eight seasons, having played 520 games hitting 537 hits in 1775 at bats. He had 38 home runs and 294 runs batted in with an average of .303. He guided his team together with MLB player Kendrys Morales to the postseason in 2005.
Cañizares sold his jersey to a fan after a game. Unbeknownst to Cañizares, the fan was a member of the United States Interests Section in Havana. As a result, Cañizares received a lifetime suspension from Cuban baseball.