B3GNT2

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UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Identifiers
Symbols B3GNT2 ; B3GN-T2; B3GNT; B3GNT-2; B3GNT1; BETA3GNT; BGNT2; BGnT-2
External IDs OMIM605581 MGI1889505 HomoloGene4797 GeneCards: B3GNT2 Gene
EC number 2.4.1.149
RNA expression pattern
PBB GE B3GNT2 219326 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10678 53625
Ensembl ENSG00000170340 ENSMUSG00000051650
UniProt Q9NY97 Q9Z222
RefSeq (mRNA) NM_006577 NM_001169114
RefSeq (protein) NP_006568 NP_001162585
Location (UCSC) Chr 2:
62.42 – 62.45 Mb
Chr 11:
22.83 – 22.86 Mb
PubMed search [1] [2]

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 is an enzyme that in humans is encoded by the B3GNT2 gene.[1][2][3]

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains.[3]

References[edit]

  1. ^ Zhou D, Dinter A, Gutierrez Gallego R, Kamerling JP, Vliegenthart JF, Berger EG, Hennet T (Mar 1999). "A β-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to β-1,3-galactosyltransferases". Proc Natl Acad Sci U S A 96 (2): 406–11. doi:10.1073/pnas.96.2.406. PMC 15149. PMID 9892646. 
  2. ^ Shiraishi N, Natsume A, Togayachi A, Endo T, Akashima T, Yamada Y, Imai N, Nakagawa S, Koizumi S, Sekine S, Narimatsu H, Sasaki K (May 2001). "Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase family". J Biol Chem 276 (5): 3498–507. doi:10.1074/jbc.M004800200. PMID 11042166. 
  3. ^ a b "Entrez Gene: B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2". 

Further reading[edit]