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BAI1-associated protein 3
Symbols BAIAP3 ; BAP3
External IDs OMIM604009 HomoloGene20844 GeneCards: BAIAP3 Gene
RNA expression pattern
PBB GE BAIAP3 204874 x at tn.png
PBB GE BAIAP3 216356 x at tn.png
PBB GE BAIAP3 221993 s at tn.png
More reference expression data
Species Human Mouse
Entrez 8938 545192
Ensembl ENSG00000007516 ENSMUSG00000047507
UniProt O94812 Q80TT2
RefSeq (mRNA) NM_001199096 NM_001163270
RefSeq (protein) NP_001186025 NP_001156742
Location (UCSC) Chr 16:
1.38 – 1.4 Mb
Chr 17:
25.24 – 25.26 Mb
PubMed search [1] [2]

BAI1-associated protein 3 is a protein that in humans is encoded by the BAIAP3 gene.[1][2]

This p53-target gene encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane protein and a member of the secretin receptor family. It interacts with the cytoplasmic region of brain-specific angiogenesis inhibitor 1. This protein also contains two C2 domains, which are often found in proteins involved in signal transduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest that it may be involved in synaptic functions.[2]


BAIAP3 has been shown to interact with Brain-specific angiogenesis inhibitor 1.[1]


  1. ^ a b Shiratsuchi T, Oda K, Nishimori H, Suzuki M, Takahashi E, Tokino T, Nakamura Y (Nov 1998). "Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1". Biochem Biophys Res Commun 251 (1): 158–65. doi:10.1006/bbrc.1998.9408. PMID 9790924. 
  2. ^ a b "Entrez Gene: BAIAP3 BAI1-associated protein 3". 

Further reading[edit]