BCAR1

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Breast cancer anti-estrogen resistance 1
Protein BCAR1 PDB 1wyx.png
PDB rendering based on 1wyx.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols BCAR1 ; CAS; CAS1; CASS1; CRKAS; P130Cas
External IDs OMIM602941 MGI108091 HomoloGene7674 ChEMBL: 5559 GeneCards: BCAR1 Gene
RNA expression pattern
PBB GE BCAR1 gnf1h00170 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9564 12927
Ensembl ENSG00000050820 ENSMUSG00000031955
UniProt P56945 Q61140
RefSeq (mRNA) NM_001170714 NM_001198839
RefSeq (protein) NP_001164185 NP_001185768
Location (UCSC) Chr 16:
75.26 – 75.3 Mb
Chr 8:
111.71 – 111.74 Mb
PubMed search [1] [2]

Breast cancer anti-estrogen resistance protein 1 is a protein that in humans is encoded by the BCAR1 gene.[1][2]


References[edit]

  1. ^ Dorssers LC, van Agthoven T, Dekker A, van Agthoven TL, Kok EM (Oct 1993). "Induction of antiestrogen resistance in human breast cancer cells by random insertional mutagenesis using defective retroviruses: identification of bcar-1, a common integration site". Mol Endocrinol 7 (7): 870–8. doi:10.1210/me.7.7.870. PMID 8413311. 
  2. ^ Brinkman A, van der Flier S, Kok EM, Dorssers LC (Feb 2000). "BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells". J Natl Cancer Inst 92 (2): 112–20. doi:10.1093/jnci/92.2.112. PMID 10639512. 

Further reading[edit]

External links[edit]