BCL2L14

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BCL2-like 14 (apoptosis facilitator)
Identifiers
Symbols BCL2L14 ; BCLG
External IDs OMIM606126 MGI1914063 HomoloGene49840 GeneCards: BCL2L14 Gene
RNA expression pattern
PBB GE BCL2L14 221241 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 79370 66813
Ensembl ENSG00000121380 ENSMUSG00000030200
UniProt Q9BZR8 Q9CPT0
RefSeq (mRNA) NM_030766 NM_025778
RefSeq (protein) NP_110393 NP_080054
Location (UCSC) Chr 12:
12.2 – 12.36 Mb
Chr 6:
134.4 – 134.44 Mb
PubMed search [1] [2]

Apoptosis facilitator Bcl-2-like protein 14 is a protein that in humans is encoded by the BCL2L14 gene.[1][2]

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Four alternatively spliced transcript variants, which encode three distinct isoforms, have been reported for this gene.[2]

References[edit]

  1. ^ Guo B, Godzik A, Reed JC (May 2001). "Bcl-G, a novel pro-apoptotic member of the Bcl-2 family". J Biol Chem 276 (4): 2780–5. doi:10.1074/jbc.M005889200. PMID 11054413. 
  2. ^ a b "Entrez Gene: BCL2L14 BCL2-like 14 (apoptosis facilitator)". 

Further reading[edit]