BD-1047

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BD-1047
BD-1047 structure.png
Systematic (IUPAC) name
N'-[2-(3,4-dichlorophenyl)ethyl]-N,N,N'-trimethylethane-1,2-diamine
Clinical data
Legal status
?
Identifiers
CAS number 138356-20-4 N
ATC code None
PubChem CID 188914
ChemSpider 164154 YesY
ChEMBL CHEMBL143360 YesY
Chemical data
Formula C13H20Cl2N2 
Mol. mass 275.217 g/mol
 N (what is this?)  (verify)

BD-1047 is a sigma receptor antagonist, selective for the σ1 subtype. It has effects in animal studies suggestive of antipsychotic activity and may also be useful in the treatment of neuropathic pain.[1][2]

References[edit]

  1. ^ Skuza G, Rogóz Z (2006). "Effect of BD 1047, a sigma1 receptor antagonist, in the animal models predictive of antipsychotic activity". Pharmacological Reports : PR 58 (5): 626–35. PMID 17085854. 
  2. ^ Roh DH, Kim HW, Yoon SY, Seo HS, Kwon YB, Kim KW, Han HJ, Beitz AJ, Na HS, Lee JH (November 2008). "Intrathecal injection of the sigma(1) receptor antagonist BD1047 blocks both mechanical allodynia and increases in spinal NR1 expression during the induction phase of rodent neuropathic pain". Anesthesiology 109 (5): 879–89. doi:10.1097/ALN.0b013e3181895a83. PMID 18946301.