BFSP1

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Beaded filament structural protein 1, filensin
Identifiers
Symbols BFSP1 ; CP115; CP94; CTRCT33; LIFL-H
External IDs OMIM603307 MGI101770 HomoloGene922 GeneCards: BFSP1 Gene
RNA expression pattern
PBB GE BFSP1 206746 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 631 12075
Ensembl ENSG00000125864 ENSMUSG00000027420
UniProt Q12934 A2AMT1
RefSeq (mRNA) NM_001161705 NM_001291061
RefSeq (protein) NP_001155177 NP_001277990
Location (UCSC) Chr 20:
17.49 – 17.57 Mb
Chr 2:
143.83 – 143.86 Mb
PubMed search [1] [2]

BFSP1 is a gene that encodes the protein filensin in humans.[1][2]

More than 99% of the vertebrate ocular lens is made up of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin (or CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF).[2]

References[edit]

  1. ^ Rendtorff ND, Hansen C, Silahtaroglu A, Henriksen KF, Tommerup N (Dec 1998). "Isolation of the human beaded-filament structural protein 1 gene (BFSP1) and assignment to chromosome 20p11.23-p12.1". Genomics 53 (1): 114–6. doi:10.1006/geno.1998.5478. PMID 9787085. 
  2. ^ a b "Entrez Gene: BFSP1 beaded filament structural protein 1, filensin". 

Further reading[edit]