BRE (gene)

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Brain and reproductive organ-expressed (TNFRSF1A modulator)
Identifiers
Symbols BRE ; BRCC4; BRCC45
External IDs OMIM610497 MGI1333875 HomoloGene3604 GeneCards: BRE Gene
RNA expression pattern
PBB GE BRE 205550 s at tn.png
PBB GE BRE 211566 x at tn.png
PBB GE BRE 212645 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9577 107976
Ensembl ENSG00000158019 ENSMUSG00000052139
UniProt Q9NXR7 Q8K3W0
RefSeq (mRNA) NM_001261840 NM_144541
RefSeq (protein) NP_001248769 NP_653124
Location (UCSC) Chr 2:
28.11 – 28.56 Mb
Chr 5:
31.7 – 32.08 Mb
PubMed search [1] [2]

BRCA1-A complex subunit BRE is a protein that in humans is encoded by the BRE gene.[1][2][3]


Interactions[edit]

BRE (gene) has been shown to interact with BRCA2,[4] RAD51,[4] BRCC3,[4][5] BRCA1,[4] C19orf62,[5][6] P53[4] and BARD1.[4]

References[edit]

  1. ^ Gu C, Castellino A, Chan JY, Chao MV (September 1998). "BRE: a modulator of TNF-alpha action". FASEB J 12 (12): 1101–8. PMID 9737713. 
  2. ^ Li L, Yoo H, Becker FF, Ali-Osman F, Chan JY (February 1995). "Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid". Biochem Biophys Res Commun 206 (2): 764–74. doi:10.1006/bbrc.1995.1108. PMID 7826398. 
  3. ^ "Entrez Gene: BRE brain and reproductive organ-expressed (TNFRSF1A modulator)". 
  4. ^ a b c d e f Dong, Yuanshu; Hakimi Mohamed-Ali; Chen Xiaowei; Kumaraswamy Easwari; Cooch Neil S; Godwin Andrew K; Shiekhattar Ramin (November 2003). "Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair". Mol. Cell (United States) 12 (5): 1087–99. doi:10.1016/S1097-2765(03)00424-6. ISSN 1097-2765. PMID 14636569. 
  5. ^ a b Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. 
  6. ^ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

Further reading[edit]