Bacillus clausii

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Bacillus clausii
Scientific classification
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Bacillaceae
Genus: Bacillus
Species: B. clausii
Binomial name
Bacillus clausii
Nielsen et al. 1995

Bacillus clausii is a rod-shaped, Gram-positive, motile and spore-forming bacterium which lives in the soil. It is classified as probiotic; microrganisms that maintain a symbiotic relationship with the host organism.[1] It is currently being studied in respiratory infections[2] and some gastrointestinal disorders.[3]

Genome structure[edit]

Bacillus clausii has relativelly small genome that contains 4.30 Mbp with 4,108 protein coding genes.[4]


  1. ^ Urdaci MC, Bressollier P, Pinchuk I (July 2004). "Bacillus clausii probiotic strains: antimicrobial and immunomodulatory activities". J. Clin. Gastroenterol. 38 (6 Suppl): S86–90. doi:10.1097/01.mcg.0000128925.06662.69. PMID 15220667. 
  2. ^ Marseglia GL, Tosca M, Cirillo I, et al. (March 2007). "Efficacy of Bacillus clausii spores in the prevention of recurrent respiratory infections in children: a pilot study". Ther Clin Risk Manag 3 (1): 13–7. doi:10.2147/tcrm.2007.3.1.13. PMC 1936284. PMID 18360611. 
  3. ^ Gabrielli M, Lauritano EC, Scarpellini E,et al. (May 2009). "Bacillus clausii as a treatment of small intestinal bacterial overgrowth". Am. J. Gastroenterol. 104 (5): 1327–8. doi:10.1038/ajg.2009.91. PMID 19352343. 
  4. ^ Kobayashi, T.; Hakamada, Y.; Adachi, S.; Hitomi, J.; Yoshimatsu, T.; Koike, K.; Kawai, S.; Ito, S. (Jul 1995). "Purification and properties of an alkaline protease from alkalophilic Bacillus sp. KSM-K16.". Appl Microbiol Biotechnol 43 (3): 473–81. PMID 7632397. 

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