Bacillus halodurans

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Bacillus halodurans
Scientific classification
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B. halodurans
Binomial name
Bacillus halodurans
(ex Boyer et al. 1973) Nielsen et al. 1995[1]

Bacillus halodurans is a rod-shaped, Gram-positive, motile and spore-forming bacterium found in soil. In a genomic comparison with Bacillus subtilis, B. halodurans strain C-125 - originally an unclassified Bacillus strain[2] - was found to contain unique genes and sigma factors that may have aided its adaptation to more alkaline environments.[3]

This species has been recently transferred into the genus Alkalihalobacillus. [4] The correct nomenclature is Alkalihalobacillus halodurans.

Bacteriocin production[edit]

B. halodurans produces a bacteriocin, haloduracin, that may be useful as a lantibiotic and could be produced in large quantities by solid state fermentation.[5]

Genome structure[edit]

B. halodurans has a genome that contains 4.2 Mbp with 4,066 protein coding genes.[3][6]

References[edit]

  1. ^ "Species: Bacillus halodurans". lpsn.dsmz.de.
  2. ^ Takami, Hideto; Horikoshi, Koki (1 January 1999). "Reidentification of Facultatively Alkaliphilic Bacillus sp. C-125 to Bacillus halodurans". Bioscience, Biotechnology, and Biochemistry. 63 (5): 943–945. doi:10.1271/bbb.63.943. PMID 27385575.
  3. ^ a b Takami, H. (2000). "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis". Nucleic Acids Research. 28 (21): 4317–4331. doi:10.1093/nar/28.21.4317. PMC 113120.
  4. ^ Patel, Sudip; Gupta, Radhey S. (2020-01-01). "A phylogenomic and comparative genomic framework for resolving the polyphyly of the genus Bacillus: Proposal for six new genera of Bacillus species, Peribacillus gen. nov., Cytobacillus gen. nov., Mesobacillus gen. nov., Neobacillus gen. nov., Metabacillus gen. nov. and Alkalihalobacillus gen. nov". International Journal of Systematic and Evolutionary Microbiology. 70 (1): 406–438. doi:10.1099/ijsem.0.003775. ISSN 1466-5026.
  5. ^ Danesh, A; Mamo, G; Mattiasson, B (July 2011). "Production of haloduracin by Bacillus halodurans using solid-state fermentation". Biotechnology Letters. 33 (7): 1339–44. doi:10.1007/s10529-011-0581-0. PMID 21384193.
  6. ^ Takami, H.; Nakasone, K.; Hirama, C.; Takaki, Y.; Masui, N.; Fuji, F.; Nakamura, Y.; Inoue, A. (Jan 1999). "An improved physical and genetic map of the genome of alkaliphilic Bacillus sp. C-125". Extremophiles. 3 (1): 21–8. doi:10.1007/s007920050095. PMID 10086841.

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