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Mysophobia, also known as verminophobia, germophobia, germaphobia, bacillophobia and bacteriophobia, is a pathological fear of contamination and germs. The term was coined by Dr. William Alexander Hammond in 1879 when describing a case of obsessive-compulsive disorder (OCD) exhibited in repeatedly washing one's hands. Mysophobia has long been related to the OCD of constantly washing one's hands. However, Harry Stack Sullivan, an American psychologist and psychoanalyst, notes that while fear of dirt underlies the compulsion of a person with this kind of OCD, his or her mental state is not about germs; instead, this person feels the hands must be washed. Names pertaining directly to the abnormal fear of dirt and filth include molysmophobia or molysomophobia, rhypophobia, and rupophobia, whereas the terms bacillophobia and bacteriophobia specifically refer to the fear of bacteria and microbes in general.
The term mysophobia comes from the Greek μύσος musos, "uncleanness" and φόβος phobos, "fear".