Baicalin
| Baicalin | |
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(2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenyl-chromen-7-yl)oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid |
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Other names
Baicalein 7-O-glucuronide; 5,6-Dihydroxy-4-oxygen-2-phenyl-4H-1-benzopyran-7-beta-D-glucopyranose acid |
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| Identifiers | |
| CAS number | 21967-41-9  |
| PubChem | 64982 |
| ChemSpider | 58507  |
| UNII | 347Q89U4M5 |
| ChEBI | CHEBI:2981 |
| ChEMBL | CHEMBL485818 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C21H18O11 |
| Molar mass | 446.36 g mol−1 |
| Exact mass | 446.084911 g mol−1 |
| Melting point |
202-205 °C, 475-478 K, 396-401 °F |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Baicalin is a flavone, a type of flavonoid. It is found in several species in the genus Scutellaria, including Scutellaria lateriflora (blue skullcap). There are 10 mg/g baicalin in Scutellaria galericulata (common skullcap) leaves.[1] It is a component of Chinese medicinal herb Huang-chin (Scutellaria baicalensis).
It is one of the active ingredients of Sho-Saiko-To, an herbal supplement believed to enhance liver health.
Baicalin is the glucuronide of baicalein.
Baicalin is a known prolyl endopeptidase inhibitor[2] and affects the GABA receptors.
[edit] References
- ^ P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
- ^ Tarragó T, Kichik N, Claasen B, Prades R, Teixidó M, Giralt E. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. Bioorganic and Medicinal Chemistry. 2008 Aug 1;16(15):7516-24. PMID 18650094
[edit] External links
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