|Prince Akbar and Noblemen Hawking, Probably Accompanied by His Guardian Bairam Khan|
|Regent of the Mughal Emperor|
|Died||31 January 1561
Gujarat, Mughal Empire
|Years of service||c. 1517-1561|
|Battles/wars||Battle of Khanwa
Battle of Ghaghra
Siege of Sambhal
Second Battle of Panipat
Bairam Khan also Bayram Khan (Persian: بيرام خان) (died 1561) was an important military commander, among top generals, later commander in chief of the Mughal army, a powerful statesman and regent at the court of the Mughal emperors Humayun and Akbar, also guardian, chief mentor, advisor, teacher and most trusted person of Humayun. Humayun honored him as Khan Khanan,means king of kings. Bairam actually was not "Khan",his real name was Bairam "Beg".Shah of Iran,Tamasp,honored him as 'Kha' or Khan. 
Bairam Khan was born in Badakhshan, now in present day Afghanistan, and belonged to the Baharlu clan of the Turkmen Kara Koyunlu tribe. The Kara Koyunlu had ruled Western Persia for decades before being overthrown by their Ak Koyunlu rivals. Bairam Khan's father and grandfather had previously joined in Babur's service.
Bairam entered Babur's service at the age of 16 and played an active role in the early Mughal conquests of India. Bairam Khan later contributed greatly to the establishment of the Mughal empire under Humayun. Under Humayan he was entrusted the position of muhradr (keeper of the seals) and took part in military campaigns in Benares, Bengal and Gujarat. He accompanied Humayun during his exile in Persia and helped conquer Kandahar before serving as its governor for nine years. In 1556, he played a leading role as a commander in Humayun's reconquest of Hindustan.
Following Humayun's death in 1556, Bairam Khan was appointed Regent over the young monarch Akbar. As regent, he consolidated Mughal authority in northern India and most notably led Mughal forces at the Second Battle of Panipat, which was fought between Akbar and the Hindu king Hemu in Nov. 1556.
Bairam Khan was a Shia muslim and was disliked by the Sunni Turkic nobles. Bairam was dismissed from Akbar's service in 1560 As he was defeated badly by Kunwar Partap(young Maharana Pratap) and left alive by Kunwar Pratap in a very injured and defamatory position. He subsequently chose to leave India to perform the hajj pilgrimage in Mecca.
While travelling through Gujarat, he was assassinated by Hazi Khan Mewati of Alwar, who was the General and close confidant of Hindu Kings of North India Hemu, and was staying at Patan after Akbar's forces captured Alwar Sarkar in 1559. One day when Bairam Khan was at Sahstraling Talav, a religious site, he was recognised by Lohani Pashtun an associate of Hazi Khan Mewati, whose father had been killed in Second Battle of Panipat (1556), five years ago, which was led by Bairam Khan. Hazi Khan attacked and killed Bairam Khan, to take the revenge of his father's death and due to jealousy towards him, being a Shia muslim. Bairam Khan died on 31 January 1561. However, his son and wife were allowed to go free and sent to north India. Bairam Khan's wife, who was also the cousin of Akbar, married Akbar after Bairam Khan's death and later on Bairam's son, Abdul Rahim Khan-i-khana, got an important assignment in Akbar's administration and was one of the 'Nau-rattans' (Nine Gems) of Akbar.
Marriage with Khanzada Jamal Khan's Daughter
Gazetteer of Ulwur states:
Soon after Babar's death, his successor, Humayun, was in A.D. 1540 supplanted by the greedy power hungry Sher Shah, who, in A.D. 1545, was followed by Islam Shah. During the reign of the latter a battle was fought and lost by the Emperor's troops at Firozpur Jhirka, in Mewat, on which, however, Islam Shah did not loose his hold. Adil Shah, the third of the Pathan interlopers, who succeeded in A.D. 1552, had to contend for the Empire with the returned Humayun.Full text of "The Imperial Gazetteer of India, Volume- XXI. Retrieved 2014-01-11.</ref>
In these struggles for the restoration of Babar's dynasty Khanzadas apparently do not figure at all. Humayun seems to have conciliated them by marrying the elder daughter of Jamal Khan, nephew of Babar's opponent, Hasan Khan, and by causing his great minister, Bairam Khan, to marry a younger daughter of the same Mewatti.
His other wife was Salima Sultan Begum, who married Akbar after his death.
- Thackston, Wheeler M. (2002) The Baburnama: Memoirs of Babur, Prince and Emperor The Modern Library, New York, page xix, ISBN 0-375-76137-3
- Ahmed,Humayun,(2011) Badsha Namdar,National Library,Dhaka,page 200-233 ISBN 978-984-502-017-6
- Ray, Sukumar & Beg, M.H.A. (1992) Bairam Khan, Mirza Beg, 1992, page 11, ISBN 969-8120-01-7
- Ray, Sukumar & Beg, M.H.A. (1992) Bairam Khan, Mirza Beg, 1992, page 27, ISBN 969-8120-01-7
- Rahim-Abdul Rahim Khankhana at Indiagrid
- Bose, Mandakranta. Faces of the Feminine in Ancient, Medieval, and Modern India, 2000.
- Singh, Damodar (2003) Khan-i-Khanan Bairam Khan: a political biography Janaki Prakashan, Patna, India, OCLC 54054058
- Shashi, Shyam Singh (1999) Bairam Khan : soldier and administrator (Series Encyclopaedia Indica volume 58) Anmol Publishing, New Delhi, India, OCLC 247186335
- Pandey, Ram Kishore (1998) Life and achievements of Muhammad Bairam Khan Turkoman Prakash Book Depot, Bareilly, India, OCLC 5007653.
- Ray, Sukumar (1992) Bairam Khan Institute of Central and West Asian Studies, University of Karachi, Karachi, Pakistan, OCLC 29564939.
- Agravāla, Sushamā Devī (1994) Bairamakhām̐ aura usake vaṃśaja kā Mugala sāmrājya meṃ yogadāna Rāmānanda Vidyā Bhavana, New Delhi, India, OCLC 34118191, in Hindi. (Contribution of Bairam Khan, 1524?-1561, Mogul nobleman, to the Mogul Empire.)
- Devīprasāda, Munśī (2001) Khānakhānā nāmā Pratibhā Pratishṭhāna, New Delhi, India, ISBN 81-85827-89-3, in Hindi. (On the life and achievements of Bairam Khan, 1524?-1561, ruler in the Mogul Empire and Khane Khana Abdul Rahim Khan, 1556–1627, Braj poet.)
- Ahmed,Humayun (2011) Badsha Namdar,Dhaka,Bangladesh, ISBN 978-984-502-017-6