The Barton reaction involves the photolysis of a nitrite to form a δ-nitroso alcohol. It is named for the British chemist Sir Derek Harold Richard Barton. The mechanism is believed to involve a homolytic RO–NO cleavage, followed by δ-hydrogen abstraction and free radical recombination.
A related reaction is the Hofmann-Löffler reaction involving haloamines.
- Barton, D. H. R.; Beaton, J. M.; Geller, L. E.; Pechet, M. M. (1961). "A New Photochemical Reaction1". Journal of the American Chemical Society 83 (19): 4076–4083. doi:10.1021/ja01480a030.
- IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "Barton Reaction".