In the developing nervous system, the basal plate is the region of the neural tube ventral to the sulcus limitans. It extends from the rostral mesencephalon to the end of the spinal cord and contains primarily motor neurons, whereas neurons found in the alar plate are primarily associated with sensory functions. The cell types of the basal plate include lower motor neurons and four types of interneuron.[1]
Initially the left and right sides of the basal plate are continuous, but during neurulation they become separated by the floor plate, a derivative of the notochord. Differentiation of neurons in the basal plate is under the influence of the protein Sonic hedgehog released by ventralizing structures such as the notochord and floor plate[1].
[edit] References
- ^ a b Bruce M. Carlson (2004). Human Embryology and Developmental Biology (2nd edition ed.). Saint Louis, MO: Mosby. ISBN 0-323-03649-X.
[edit] Bibliography
- John A. Kiernan (2005). Barr's the Human Nervous System: An Anatomical Viewpoint (8th edition ed.). Hagerstown, MD: Lippincott Williams & Wilkins. ISBN 0-7817-5154-3.
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