By forced marching, on a rainy November 16, Maj. Gen. Ambrose E. Burnside's advance reached the vital intersection and deployed first. The main column arrived at noon with the baggage train just behind. Scarcely 15 minutes later, Longstreet's Confederates approached. Longstreet attempted a double envelopment: attacks timed to strike both Union flanks simultaneously. Maj. Gen. Lafayette McLaws's Confederate division struck with such force that the Union right had to redeploy, but held. Brig. Gen. Micah Jenkins's Confederate division maneuvered ineffectively as it advanced and was unable to turn the Union left. Burnside ordered his two divisions astride the Kingston Road to withdraw three-quarters of a mile to a ridge in their rear. This was accomplished without confusion. The Confederates suspended their attack while Burnside continued his retrograde movement to Knoxville. Estimated casualties for the battle were 400 for the U.S. and 570 for the Confederates. Had Longstreet reached Campbell's Station first, the Knoxville Campaign's results might have been different.
Campbell's Station was incorporated as Farragut in 1982. The Old Campbell's Station Inn was built by Judge David Campbell in 1810 and is still in use as a private residence. The inn was a favorite of President Andrew Jackson, who stayed there whenever he passed through the area.