Bay R 1531

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Bay R 1531
BayR1531 structure.png
Systematic (IUPAC) name
1,3,4,5-tetrahydro-6-methoxy-N,N-dipropyl-benz[cd]indol-4-amine
Clinical data
Legal status ?
Identifiers
CAS number 98770-54-8
ATC code ?
PubChem CID 127153
ChemSpider 112872
Chemical data
Formula C18H28N2O 
Mol. mass 288.427 g/mol

Bay R 1531 is a tricyclic tryptamine derivative which acts as a selective serotonin receptor 5-HT1A agonist. It was researched unsuccessfully for the treatment of stroke but remains in use for scientific research.[1][2][3][4]

See also[edit]

References[edit]

  1. ^ Bielenberg GW, Burkhardt M. 5-hydroxytryptamine1A agonists. A new therapeutic principle for stroke treatment. Stroke. 1990 Dec;21(12 Suppl):IV161-3. PMID 2148035
  2. ^ Critchley MA, Njung'e K, Handley SL. Actions and some interactions of 5-HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions. Psychopharmacology (Berlin). 1992;106(4):484-90. PMID 1533721
  3. ^ Canto de Souza A, Nunes de Souza RL, Péla IR, Graeff FG. High intensity social conflict in the Swiss albino mouse induces analgesia modulated by 5-HT1A receptors. Pharmacology, Biochemistry and Behavior. 1997 Mar;56(3):481-6. PMID 9077586
  4. ^ Canto-de-Souza A, Nunes de Souza RL, Pelá IR, Graeff FG. Involvement of the midbrain periaqueductal gray 5-HT1A receptors in social conflict induced analgesia in mice. European Journal of Pharmacology. 1998 Mar 26;345(3):253-6. PMID 9592023