Worley was raised on the island of Maui and currently resides in the San Francisco Bay Area. She is a rugby fan, plays the ukulele, and loves to flyfish. On January 5, 2008, she gave birth to twins - Emalia and Finn Worley Mitchell.
Worley worked for KOMO-TV news in Seattle from 1993 through 1996. She left to consult on web design and information technology for small business.
She then spent 6 years (1998–2005) with ZDTV / TechTV. Worley is probably best known for being TechLive's Computer Security Analyst. She reported, anchored the news, and hosted a how-to show for TechTV. Worley wrote TechTV's Security Alert: Stories of Real People Protecting Themselves from Identity Theft, Viruses, and Scams (TechTV, November, 2003) (ISBN 0-7357-1352-9).
In 2004, Worley hosted a series on the National Geographic Channel called Mother of All, a show in which fine arts and industrial arts were blended together using whatever material was available to make the "Mother of All" things. Worley began on ABC's Good Morning America in 2005, and has appeared on their Weekend Edition starting in 2011. She has appeared as a Technology Contributor for ABC Evening News since 2011. She has been with Yahoo! Tech since 2006 as a video blogger and host of the weekly web broadcast Hook Me Up. From 2006 through 2007, she hosted a show for the Travel Channel called The Best Places to Find Cash and Treasures. She spent part of 2010 as a co-host to Tom Merritt on a daily podcast in the TWiT.tv network called Tech News Today.