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Systematic (IUPAC) name
2-(diethylamino)ethyl hydroxy(diphenyl)acetate
Clinical data
AHFS/ International Drug Names
Legal status
  • Prescription only
Routes Oral
CAS number 302-40-9 YesY
ATC code None
PubChem CID 9330
ChemSpider 8966 YesY
UNII 595EG71R3F YesY
KEGG D07498 YesY
Chemical data
Formula C20H25NO3 
Mol. mass 327.417 g/mol
 YesY (what is this?)  (verify)

Benactyzine (Suavitil, Phebex, Phobex, Cedad, Cevanol, Deprol, Lucidil, Morcain, Nutinal, Parasan) is an anticholinergic drug used as an antidepressant in the treatment of depression and associated anxiety.[1] However, its use for these indications is limited by side effects such as dry mouth and nausea, and at high doses it can cause more severe symptoms such as deliriant and hallucinogenic effects. Consequently, it is no longer widely used in medicine, although it is still a useful drug for scientific research. It does not possess any antihistamine properties.


Benactyzine synthesis:[2]

See also[edit]

3-Quinuclidinyl benzilate


  1. ^ McLaughlin, B.; Rickels, K.; Abidi, M.; Toro, R. (1969). "Meprobamate-Benactyzine (Deprol) and Placebo in two Depressed Outpatient Populations". Psychosomatics 10 (2): 73–81. doi:10.1016/S0033-3182(69)71765-0. PMID 4891208. 
  2. ^ Blicke, F. F. (1942). "Synthetic Mydriatics. I". Journal of the American Chemical Society 64 (2): 428–431. doi:10.1021/ja01254a052.  edit