Benorilate

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Benorilate
Benorilate.svg
Systematic (IUPAC) name
4-(acetylamino)phenyl 2-(acetyloxy)benzoate
Clinical data
Legal status ?
Routes Oral
Identifiers
CAS number 5003-48-5 N
ATC code N02BA10
PubChem CID 21102
ChemSpider 19846 N
UNII W1QX9DV96G YesY
ChEMBL CHEMBL162036 N
Chemical data
Formula C17H15NO5 
Mol. mass 313.305 g/mol
 N (what is this?)  (verify)

Benorilate (INN), or benorylate, is an ester-linked codrug of aspirin with paracetamol. It is used as an anti-inflammatory and antipyretic medication. In the treatment of childhood fever, it has been shown to be inferior to paracetamol and aspirin taken separately. In addition, because it is converted to aspirin, benorylate is not recommended in children due to concerns about Reye syndrome.[1]

References[edit]

  1. ^ Simila S, Keinanen S, Kouvalainen K.Oral antipyretic therapy: evaluation of benorylate, an ester of acetylsalicylic acid and paracetamol. Eur J Pediatr. 1975 Dec 9;121(1):15-20. PMID 2478