Bentiromide

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"Chymex" redirects here. For the human body digestive fluid, see Chyme.
Bentiromide[1]
Bentiromide.svg
Names
IUPAC name
4-[2-benzamido-3- (4-hydroxyphenyl)- propanoyl] aminobenzoic acid
Other names
(S)-4-((2-(benzoylamino)-3-(4-hydroxyphenyl) -1-oxopropyl)amino)benzoic acid
(S)-p-(α-benzamido-p-hydroxyhydrocinnamamido) benzoic acid
Benzoyltyrosyl-p-aminobenzoic acid (Btpaba)Chymex
N-benzoyl-L-tyrosyl-p-aminobenzoic acid
P-((N-benzoyl-L-tyrosin)amido)benzoic acid
Identifiers
Abbreviations Btpaba
ATC code V04CK03
37106-97-1 YesY
ChEBI CHEBI:31263 YesY
ChEMBL ChEMBL1200368 N
ChemSpider 5329364 YesY
EC number 253-349-8
Jmol-3D images Image
PubChem 6957673
UNII 239IF5W61J YesY
Properties
C23H20N2O5
Molar mass 404.4153 g/mol
Pharmacology
DrugBank DB00522 YesY
Supplementary data page
Refractive index (n),
Dielectric constantr), etc.
Thermodynamic
data
Phase behaviour
solid–liquid–gas
UV, IR, NMR, MS
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Bentiromide is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. It is given by mouth as a noninvasive test. The amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas. Headache and gastrointestinal disturbances have been reported in patients taking bentiromide. Bentiromide is not available in the U.S. or Canada (It was withdrawn in the US in October 1996.)

Data[edit]

  • XLogP=3.201
  • tautomers=12
  • H_bond_donor=4
  • H_bond_acceptor=5

See also[edit]

References[edit]