Benzathine benzylpenicillin
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|---|---|
| Combination of | |
| Benzylpenicillin | Antibiotic |
| Benzathine | Stabilizer |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 1538-09-6  |
| ATC code | J01CE08 |
| PubChem | CID 15232 |
| UNII | SSZ1S4I0US |
| ChEMBL | CHEMBL1200651 |
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Benzathine benzylpenicillin (rINN) is a form of penicillin also known as benzathine penicillin. It is slowly absorbed into the circulation, after intramuscular injection, and hydrolysed to benzylpenicillin in vivo. It is the drug-of-choice when prolonged low concentrations of benzylpenicillin are required and appropriate, allowing prolonged antibiotic action over 2–4 weeks after a single IM dose. It is marketed by Wyeth under the trade name Bicillin L-A.
Specific indications for benzathine penicillin include:[1]
- Prophylaxis of rheumatic fever
- Early or latent syphilis
Adverse effects [edit]
Further information: Penicillin drug reaction
Compendial status [edit]
References [edit]
- ^ Rossi S, editor, ed. (2006). Australian Medicines Handbook. Adelaide: Australian Medicines Handbook. ISBN 0-9757919-2-3.
- ^ British Pharmacopoeia Commission Secretariat. "Index (BP 2009)". Retrieved 26 March 2010.
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