Benzathine benzylpenicillin

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Benzathine benzylpenicillin
Benzylpenicillin-Benzathin Structural Formula V.1.svg
Combination of
Benzylpenicillin Antibiotic
Benzathine Stabilizer
Clinical data
AHFS/Drugs.com International Drug Names
Legal status ?
Identifiers
CAS number 1538-09-6 N
ATC code J01CE08
PubChem CID 15232
ChemSpider 14498 N
UNII SSZ1S4I0US N
ChEBI CHEBI:51352 N
ChEMBL CHEMBL1200651 N
 N (what is this?)  (verify)

Benzathine benzylpenicillin (rINN) is a form of penicillin also known as benzathine penicillin. It is an antibiotic useful for the treatment of a number of bacterial infections.

It is slowly absorbed into the circulation, after intramuscular injection, and hydrolysed to benzylpenicillin in vivo. It is the drug-of-choice when prolonged low concentrations of benzylpenicillin are required and appropriate, allowing prolonged antibiotic action over 2–4 weeks after a single IM dose. It is marketed by Wyeth under the trade name Bicillin L-A.

Medical uses for benzathine penicillin include: prevention of rheumatic fever and early or latent syphilis.[1]

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.[2]

Adverse effects[edit]

Further information: Penicillin drug reaction

Compendial status[edit]

References[edit]

  1. ^ Rossi S, editor, ed. (2006). Australian Medicines Handbook. Adelaide: Australian Medicines Handbook. ISBN 0-9757919-2-3. 
  2. ^ "WHO Model List of EssentialMedicines". World Health Organization. October 2013. Retrieved 22 April 2014. 
  3. ^ British Pharmacopoeia Commission Secretariat. "Index (BP 2009)". Retrieved 26 March 2010.