Benzisothiazolinone
| Benzisothiazolinone | |
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1,2-benzisothiazol-3(2H)-one |
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Other names
Benzisothiazolinone, Benzisothiazolin-3-one, Benzisothiazolone |
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| Identifiers | |
| Abbreviations | BIT |
| CAS number | 2634-33-5  |
| PubChem | 17520 |
| ChemSpider | 16567 |
| MeSH | 1,2-benzisothiazoline-3-one |
| ChEBI | CHEBI:167099 |
| ChEMBL | CHEMBL297304 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C7H5NOS |
| Molar mass | 151.19 g mol−1 |
| Appearance | white powder |
| Melting point |
158 °C [1] |
| Solubility in water | 1 g/l |
| Hazards | |
| R-phrases | R22, R38, R41, R43, R50 [1] |
| S-phrases | (S2), S24, S26, S37/39, S61 [1] |
| Main hazards | Xn, N [1] |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Benzisothiazolinone (BIT) is a widely used biocide and belongs to the group of isothiazolinones.
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[edit] Usage
Benzisothiazolinone has a microbicide and a fungicide mode of action. It is used as a preservative in emulsion paints, varnishes, adhesives, washing agents, fuels and in the papermaking process. In paints, it is commonly used as a mixture with methylisothiazolinone. Typical concentrations in products are 200–400 ppm depending on the application area and the combination with other biocides. According to a study in Switzerland, 19% of the paints, varnishes and coatings contained BIT in 2000. The fraction in adhesives, sealants, plasters and fillers was 25%. [2]
[edit] Health hazards
It is a known human immune system toxicant, and also is classified as irritant for skin, eyes and lungs.[3] It is widely used as active ingredient of many home cleaning products.
[edit] References
- ^ a b c d Record of 1,2-Benzisothiazol-3(2H)-one in the GESTIS Substance Database from the IFA, accessed on 22 October 2007
- ^ Reinhard et al.: "Preservation of products with MCI/MI in Switzerland". Contact Dermatitis. 2001 Nov;45(5):257-64. PMID 11722483
- ^ EWG's Skin Deep Cosmetics Database
[edit] Literature
- Wilfried Paulus: Directory of Microbicides for the Protection of Materials and Processes. Springer Netherland, Berlin 2006, ISBN 1-402-04861-0.
