Benzoxazole

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Benzoxazole
Skeletal formula with numbering convention
Full structural formula with aromatic bond
Ball-and-stick molecular model Space-filling molecular model
Identifiers
CAS number 273-53-0 YesY
PubChem 9228
ChemSpider 8873 YesY
ChEBI CHEBI:38814 YesY
ChEMBL CHEMBL451894 YesY
Jmol-3D images Image 1
Properties
Molecular formula C7H5NO
Molar mass 119.12 g mol−1
Appearance white to light yellow solid
Melting point 27 to 30 °C (81 to 86 °F; 300 to 303 K)
Boiling point 182 °C (360 °F; 455 K)
Solubility in water insol.
Hazards
Flash point 58 °C (136 °F; 331 K)
Related compounds
Related compounds oxazole
indole
benzofuran
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY (verify) (what is: YesY/N?)
Infobox references

Benzoxazole is an aromatic organic compound with a molecular formula C7H5NO, a benzene-fused oxazole ring structure, and an odor similar to pyridine.[1][2] Benzoxazole is used primarily in industry and research, and has no household use.

Being a heterocyclic compound, benzoxazole finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as flunoxaprofen.

Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.

See also[edit]

References[edit]

  1. ^ Katritzky, A. R.; Pozharskii, A. F. (2000). Handbook of Heterocyclic Chemistry (2nd ed.). Academic Press. ISBN 0080429882. 
  2. ^ Clayden, J.; Greeves, N.; Warren, S.; Wothers, P. (2001). Organic Chemistry. Oxford, Oxfordshire: Oxford University Press. ISBN 0-19-850346-6.