Bepridil

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Bepridil
Bepridil.svg
Systematic (IUPAC) name
N-benzyl-N-(3-isobutoxy-2-pyrrolidin-1-yl-propyl)aniline
Clinical data
Trade names Vascor
AHFS/Drugs.com monograph
MedlinePlus a699051
Pregnancy cat.
Legal status
?
Routes Oral
Pharmacokinetic data
Bioavailability Well absorbed
Protein binding 99%
Metabolism Hepatic, CYP3A4-mediated
Half-life 42 hours
Excretion Renal
Identifiers
CAS number 64706-54-3 YesY
ATC code C08EA02
PubChem CID 2351
IUPHAR ligand 2337
DrugBank DB01244
ChemSpider 2261 YesY
UNII 755BO701MA YesY
ChEBI CHEBI:3061 YesY
ChEMBL CHEMBL1008 YesY
Chemical data
Formula C24H34N2O 
Mol. mass 366.54 g/mol
 YesY (what is this?)  (verify)

Bepridil (trade name Vascor) is a calcium channel blocker once used to treat angina. It is no longer sold in the United States.

It is nonselective.[1]

It has been discussed as a possible option in the treatment of atrial fibrillation.[2]

It has been implicated in causing ventricular arrhythmia (Torsade de pointes).

References[edit]

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