Bereina is a town in the Central Province of Papua New Guinea. It is located on the Hiritano Highway about 160 kilometres (100 mi) northwest of Port Moresby, and contains the headquarters of both the Kairuku-Hiri District and the Kairuku Rural local-level government area. Bereina also hosts a regional airport.
Bereina is home to three elementary schools and one primary school. A short distance to the south is Mainohana Catholic High School, a De La Salle Year 9–12 school established in 1958.