Best Brains, Inc. (first known as Hair Brain Productions) is an entertainment company based in Eden Prairie, Minnesota. It is best known for its creation and production of the comedy/sci-fi television program Mystery Science Theater 3000, aka MST3K (1988–1999). The company ceased producing the program in 1999 and closed its studio. Currently, its only functions are to sell MST3K-oriented merchandise and negotiate home video releases through Shout! Factory as well as video on demand via Hulu and Netflix.
According to Joel Hodgson, the name "Best Brains" came from "...a phrase I found in a magic catalog. It was the old 'Vick Lawston' magic catalog. The copy read something like: 'from some of the Best Brains in the magic business!'"
On November 5, 2007, Jim Mallon and Paul Chaplin of Best Brains revived the MST3K brand by launching a new series of Flash-based animated shorts featuring the robots of Mystery Science Theater 3000 on the official website. The series was ended after several months due to cost issues.