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CAS number 35597-43-4 YesY
PubChem 5462314
ChemSpider 4575372 YesY
Jmol-3D images Image 1
Molecular formula C11H22N3O6P
Molar mass 323.28 g mol−1
Density 1.33 g/mL
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Bialaphos is a natural herbicide produced by the bacteria Streptomyces hygroscopicus[1] and Streptomyces viridochromeogenes.

Biapahos is made up of two alanine residues and the glutamic acid analog phosphinothricin and is commonly used as a gene sector in plants. Resistance plasmids include: pGreenII 0229 and pGreenII 0229 62-SK. pGreenII 0229 is derived from pGreenII 0000, a nos-bar cassette has been inserted into the HpaI site of the Left Border, providing resistance to bialaphos or phosphinothricin during plant transformation selection. pGreenII 0229 62-SK is derived from pGreenII 0229, the LacZ blue/white cloning selection has been replaced with a 35S-MCS-CaMV cassette that allows the insertion of a gene of interest into a 35S over-expression cassette.[2]


  1. ^ Murakami, Takeshi; Anzai, Hiroyuki; Imai, Satoshi; Satoh, Atsuyuki; Nagaoka, Kozo; Thompson, Charles J. (1986). "The bialaphos biosynthetic genes of Streptomyces hygroscopicus: Molecular cloning and characterization of the gene cluster". MGG Molecular & General Genetics 205: 42. doi:10.1007/BF02428031. 
  2. ^ "Bialaphos as plant gene selector". Retrieved 20 June 2012.