Bifidobacterium animalis

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Bifidobacterium animalis
Scientific classification
Kingdom: Bacteria
Division: Firmicutes
Class: Actinobacteria
Order: Bifidobacteriales
Family: Bifidobacteriaceae
Genus: Bifidobacterium
Species: B. animalis
Binomial name
Bifidobacterium animalis
(Mitsuoka 1969)
Scardovi and Trovatelli 1974

B. a. animalis
B. a. lactis

Bifidobacterium animalis is a Gram-positive anaerobic rod-shaped bacterium which can be found in the large intestines of most mammals, including humans.

Bifidobacterium animalis and Bifidobacterium lactis were previously described as two distinct species. Presently, both are considered B. animalis with the subspecies Bifidobacterium animalis subsp animalis and Bifidobacterium animalis subsp lactis.[1][2][3]

Both old names B. animalis and B. lactis are still used on product labels, as this species is frequently used as a probiotic. In most cases it is not clear which subspecies is used in the product.

Trade names[edit]

Several companies have attempted to trademark particular strains and, as a marketing technique, have invented scientific sounding names for the strains.

Danone (Dannon) markets the subspecies strain DN 173 010 as Bifidus Digestivum (UK), Bifidus Regularis (US and Mexico), Bifidobacterium Lactis or B.L. Regularis (Canada), DanRegularis (Brazil), Bifidus Actiregularis (Argentina, Austria, Belgium, Bulgaria, Chile, Czech Republic, France, Germany, Greece, Hungary, Israel, Italy, Kazakhstan, Netherlands, Portugal, Romania, Russia, South Africa, Spain and the UK), and Bifidus Essensis in the Middle East (and formerly in Hungary and Bulgaria) through Activia from Safi Danone KSA.[citation needed]

Chr. Hansen A/S [4] from Denmark has a similar claim on a strain of Bifidobacterium animalis subsp. lactis, marketed under the trademark BB-12.[5]

Lidl lists "Bifidobacterium BB-12" in its "Proviact" yogurt.

Therelac contains the strains "Bifidobacterium lactis BI-07" and "Bifidobacterium lactis BL-34" (also called BI-04) in its probiotic capsule.[6]

The strain "Bifidobacterium lactis HN-019" is sold in a variety of commercial probiotics, among them Attune Wellness Bars[7] and NOW Foods Clinical GI Probiotic. [8]

Health effects[edit]

Bifidobacterium animalis subsp. lactis, strain BB-12:[9]

BB-12® has been described in more than 300 scientific publications out of which more than 140 are clinical studies. BB-12® has proven effect within gastrointestinal and immune function and has been tested in newborn preterm infants to elderly people within various areas.[10]

  • Chatterjee, et al. Randomised Placebo-controlled Double Blind Multicentric Trial on Efficacy and Safety of Lactobacillus acidophilus LA-5® and Bifidobacterium BB-12® for Prevention of Antibiotic-Associated Diarrhoea. JAPI 2013;61:708–712
  • Smith, et al. Effect of Lactobacillus rhamnosus LGG® and Bifidobacterium animalis ssp. lactis BB-12® on health-related quality of life in college students affected by upper respiratory infections. Br.J.Nutr. 2013;109(11):1999–2007
  • Pitkala, et al. Fermented cereal with specific bifidobacteria normalizes bowel movements in elderly nursing home residents. A randomized, controlled trial. J.Nutr.Health Aging 2007;11:305–311

Bifidobacterium animalis subsp. animalis, strain DN-173 010:

  • A fermented milk with a Bifidobacterium probiotic strain DN-173 010 shortened oro-fecal gut transit time in elderly. Microb Ecology Health Dis,2001; 13: 217–222.
  • Bifidobacterium animalis, strain DN-173 010 shortens the colonic transit time in healthy women. A double-blind randomised controlled study. Aliment Pharmacol Ther, 2002; 16: 587–593.
  • Bouvier M, et al. “Effects of consumption of a milk fermented by the probiotic Bifidobacterium animalis DN-173 010 on colonic transit time in healthy humans. Bioscience and Microflora, 2001; Vol 20(2): 43–48.

Bifidobacterium animalis subsp. lactis, strain HN-019:

  • H. S. Gill, K. J. Rutherfurd, J. Prasad and P. K. Gopal (2000). Enhancement of natural and acquired immunity by Lactobacillus rhamnosus (HN001), Lactobacillus acidophilus (HN017) and Bifidobacterium lactis (HN019). British Journal of Nutrition, 83, pp 167-176. doi:10.1017/S0007114500000210. [11]
  • Ahmed M, Prasad J, Gill H, Stevenson L, and Gopal P. (2007). Impact of consumption of different levels of Bifidobacterium lactis HN019 on the intestinal microflora of elderly human subjects. J Nutr Health Aging. 2007 Jan-Feb;11(1):26-31.[12]

Bifidobacterium animalis subsp. lactis, strain BI-07:

  • Leyer, et al (2009). Probiotic Effects on Cold and Influenza-Like Symptom Incidence and Duration in Children. Pediatrics Vol. 124 No. 2 pp. e172 -e179(doi: 10.1542/peds.2008-2666) [13]
  • Tamar, et al (2011). Probiotic Bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 Versus Placebo for the Symptoms of Bloating in Patients With Functional Bowel Disorders: A Double-blind Study. Journal of Clinical Gastroenterology: July 2011 - Volume 45 - Issue 6 - p 518–525 doi: 10.1097/MCG.0b013e31820ca4d6 [14]

Bifidobacterium animalis subsp. lactis, strain MB-5:

  • Roselli, et al (2006). Probiotic bacteria Bifidobacterium animalis MB5 and Lactobacillus rhamnosus GG protect intestinal Caco-2 cells from the inflammation-associated response induced by enterotoxigenic Escherichia coli K88. British Journal of Nutrition / Volume 95 / Issue 06 / June 2006, pp 1177-1184. [15]


  1. ^ Bifidobacterium
  2. ^ Masco, Liesbeth; Marco Ventura, Ralf Zink, Geert Huys1 and Jean Swings (July 2004). "Polyphasic taxonomic analysis of Bifidobacterium animalis and Bifidobacterium lactis reveals relatedness at the subspecies level: reclassification of Bifidobacterium animalis as Bifidobacterium animalis subsp. animalis subsp. nov. and Bifidobacterium lactis as Bifidobacterium animalis subsp. lactis subsp. nov.". Int J Syst Evol Microbiol 54 (part 4): 1137–1143. doi:10.1099/ijs.0.03011-0. PMID 15280282. Retrieved 2007-07-14. 
  3. ^ Rapid Identification, Differentiation, and Proposed New Taxonomic Classification of Bifidobacterium lactis. Appl Environ Microbiol. 2002 December; 68(12): 6429–6434.
  4. ^
  5. ^
  6. ^
  7. ^
  8. ^
  9. ^
  10. ^
  11. ^
  12. ^
  13. ^
  14. ^
  15. ^

External links[edit]

  • – A deconstruction of the terms Bifidus Actiregularis, Bifidus Regularis, Bifidus Digestivum, L. Casei Immunitas and their variants, as well as the marketing strategy, and information about the potential health benefits of live yoghurts.
  • – How to select a probiotic