Bifonazole

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Bifonazole
Bifonazole.svg
Systematic (IUPAC) name
(RS)-1-[Phenyl(4-phenylphenyl)methyl]-1H-imidazole
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
Routes topic
Identifiers
CAS number 60628-96-8 YesY
ATC code D01AC10
PubChem CID 2378
DrugBank DB04794
ChemSpider 2287 YesY
UNII QYJ305Z91O YesY
KEGG D01775 YesY
ChEBI CHEBI:31286 YesY
ChEMBL CHEMBL277535 YesY
Chemical data
Formula C22H18N2 
Mol. mass 310.392 g/mol
 YesY (what is this?)  (verify)

Bifonazole is an imidazole antifungal drug. Bifonazole is marketed by Bayer under the trade mark Canespor in ointment form.

Mechanism of action[edit]

Bifonazole has dual mode of action. It blocks transformation of 24-methylendihydrolanosterol to desmethylsterol in fungi together with inhibition of HMG-CoA. This enables fungicidal properties against dermatophytes and distinguishes bifonazole from other antifungal drugs.