Biomolecular complex, also called macromolecular complex or biomacromolecular complex, is any biological complex made of more than one molecule of protein, RNA, DNA,  lipids, carbohydrates. The interactions between these biomolecules are non-covalent. Examples:
- protein complexes: proteasome, DNA polymerase III holoenzyme, RNA polymerase II holoenzyme, symmetric viral capsids, complex of GroEL and GroES, photosystem I, ATP synthase
- RNA and protein complexes: ribosome, spliceosome, vault, SnRNP. Such complexes in cell nucleus are called ribonucleoproteins (RNPs).
- DNA and protein complexes: nucleosome
- Protein and lipid complexes: nuclear pore
The biomacromolecular complexes are studied structurally by X-ray crystallography, NMR spectroscopy of proteins, cryo-electron microscopy and successive single particle analysis, and electron tomography.  The atomic structure models obtained by X-ray crystallography and biomolecular NMR spectroscopy can be docked into the much larger structures of biomolecular complexes obtained by lower resolution techniques like electron microscopy, electron tomography, and small-angle X-ray scattering. 
- Organelle: the broadest definition of "organelle" includes not only membrane bound cellular structures, but also very large biomolecular complexes.
- Kleinjung, Jens; Franca Fraternali (2005-07-01). "POPSCOMP: an automated interaction analysis of biomolecular complexes". Nucleic Acids Research 33 (suppl 2): W342–W346. doi:10.1093/nar/gki369. ISSN 0305-1048. Retrieved 2013-11-14.
- Russell, Robert B; Frank Alber; Patrick Aloy; Fred P Davis; Dmitry Korkin; Matthieu Pichaud; Maya Topf; Andrej Sali (June 2004). "A structural perspective on protein–protein interactions". Current Opinion in Structural Biology 14 (3): 313–324. doi:10.1016/j.sbi.2004.04.006. ISSN 0959-440X. Retrieved 2013-04-13.
- van Dijk, Aalt D. J.; Rolf Boelens, Alexandre M. J. J. Bonvin (2005). "Data-driven docking for the study of biomolecular complexes". FEBS Journal 272 (2): 293–312. doi:10.1111/j.1742-4658.2004.04473.x. ISSN 1742-4658. Retrieved 2013-11-14.