Biopterin
| Biopterin | |
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2-Amino-6-(1,2-dihydroxypropyl)-1H-pteridin-4-one |
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| Identifiers | |
| CAS number | 22150-76-1 |
| PubChem | 445040 |
| ChemSpider | 392795 |
| KEGG | C06313 |
| MeSH | Biopterin |
| Jmol-3D images | Image 1 Image 2 |
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| Properties | |
| Molecular formula | C9H11N5O3 |
| Molar mass | 237.216 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Biopterin is a coenzyme that is produced within the body.
It is an oxidized degradation product of tetrahydrobiopterin.
Defects in biopterin synthesis or regeneration can cause a form of hyperphenylalaninemia (a disease with symptoms similar to PKU) [1].
Biopterin is synthesized in several parts of the body, including the pineal gland[2].
Biopterin deficiency has been associated with a variety of disorders, including dystonia [3] and rabies[4].
[edit] References
- ^ Tetrahydrobiopterin
- ^ Biosynthesis of biopterin: adrenergic cyclic adenosine monophosphate-dependent inhibition in the pineal gland - Kapatos et al. 213 (4512): 1129 - Science
- ^ Dystonia with marked diurnal variation associated with biopterin deficiency - Fink et al. 38 (5): 707 - Neurology [http://www.ncbi.nlm.nih.gov/pubmed/2452381 PubMed
- ^ Rodney E. Willoughby, Jr., "A Cure for Rabies?" Scientific American, V. 256, No. 4, April 2007, p. 95 (online link)
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