|Key people||Christoph Böhmer, Lothar Krings|
Biotronik (Biotronik SE & Co. KG; Biotronik Worldwide) is a privately held multinational biomedical technology company headquartered in Berlin, Germany.
The company offers complete solutions for diagnosis, treatment, and therapy support in the areas of heart rhythm management, electrophysiology and vascular intervention. In the area of heart rhythm management, Biotronik Home Monitoring® uses telemonitoring technology to provide doctors with up-to-date information on implant patients.
Biotronik employs more than 5,600 people worldwide in over 50 countries, with research and development activities in Europe and North America.
Biotronik began with the development of the first German implantable pacemaker (Biotronik IP-03) in 1963 by the physician Max Schaldach (1936-2001), a professor of biomedical technology at the Friedrich-Alexander-University of Erlangen-Nuremberg (FAU), and the electrical engineer Otto Franke. In the early years, the company worked to improve pacemakers' capacity and battery life and secure the connections among electrodes, pacemakers, and the heart.
In 1976, the company moved to Sieversufer 8 in Berlin-Neukölln where it still has its headquarters today. In 1979, a US production site in Lake Oswego, Oregon was built. This subsidiary resulted from the acquisition of the American pacemaker producer Stimulation Technology, Inc. At the same time, with the development and production of advanced hybrid circuitry and structural components for the medical technology industry, the company also began to develop circuits for pacemakers. In the 1980s, the dual-chamber stimulation method (DDD) was developed, leading to the manufacturing of a pacemaker that could read and react to spontaneous contractions of the atrium and better respond to them of its own accord. To this end, Biotronik developed the Diplos 03, a multi-program DDD pacemaker with bilateral telemetry, which made it a European market leader and increased its presence in South America and Asia.
In 1987, the firm moved its headquarters to Woermannkehre 1. In 1993, Biotronik began producing implantable cardioverter-defibrillators, among them the Phylax 03. Closed Loop Stimulation (CLS), which integrates the pacemaker into the body’s own regulatory system, thereby allowing it to react to patients’ changing physical and emotional states, was introduced in the 1990s. In 1991, Biotronik developed fractal coating for implantable electrodes. This coating optimizes the electrically active surface of the electrode, thereby improving its perception and stimulation properties. Biotronik remains the only manufacturer of fractal-coated electrodes.
In 1994 and 1995 respectively, Biotronik began offering a full spectrum of electrophysiology products and vascular intervention products. Biotronik also develops and produces balloon catheters and stents for the treatment of coronary artery disease. With Philos, the company has offered a complete pacemaker family with telemetry since 2000, when it received CE Mark approval for the product and also successfully implanted the first pacemaker with Home Monitoring (remote patient monitoring). In 2005, Biotronik developed Lumos, the world’s first implantable cardioverter-defibrillator capable of transmitting IEGMs (intracardial electrograms) automatically by mobile phone.
In 2007, Biotronik was given the EuroPCR 2007 Novelty Award for its innovative absorbable metal stents (AMS) by the European Association of Percutaneous Cardiovascular Interventions (EAPCI). In 2009, it was nominated for the German Future Prize for its Home Monitoring system by the German Federal Ministry of Education and Research. In 2010, Biotronik endowed the Berlin-Brandenburg Academy of Sciences and Humanities' Technical Science Prize, first awarded to Till Schlösser.
With the Lumax 540 VR-T DX in 2010, Biotronik launched the first and only single-chamber defibrillator with comprehensive atrial diagnostics worldwide. Additionally, the company entered into an exclusive international distribution partnership with the Swiss medical technology company Endosense to distribute their ablation catheter TactiCath with optical contact force.
In 2012, the company acquired the old Postfuhramt, a historical brick postal building on Berlin’s Oranienburger Strasse in the district of Mitte. Biotronik also launched BioMonitor that year, a type of mini ECG device that offers continuous monitoring and daily remote data collection. In addition, Biotronik also developed the world’s first series of implantable pacemakers and defibrillators that enable patients, including those suffering heart failure, to undergo MRI scans under certain conditions.
In 2013, Biotronik celebrated its 50th anniversary.
- Heart rhythm management: pacemakers, implantable defibrillators, electrodes, external monitoring and programming devices
- Electrophysiology: products for electrophysiological examinations and therapy, including ablation and diagnostic catheters
- Vascular intervention: products for coronary and peripheral functions including stent systems, balloon catheters and guide wires
Branches and Headquarters
- Berlin-Neukölln, company headquarters in Germany with over 2,100 employees
- Erlangen, Center for Technology and Service wit over 130 employees
- Rostock-Warnemünde, Competence Center for Stent Development and Production
- Vienna, Austria
- Baar and Bülach, Switzerland
- Vilvoorde, Belgium
- São Paulo, Brazil (since1982)
- Beijing, China
- Hørsholm, Denmark
- Rungis, France
- Bicester, Great Britain
- New Delhi, Kolkata and Mumbai, India
- Vimodrone, Italy
- Tokyo, Japan
- Toronto, Canada
- Poznan, Poland
- Seoul und Mapo-gu, South Korea
- Prague-Nusle, Czech Republic
- Lake Oswego, Oregon, USA
Products and Therapies
- Bradycardia therapy: pacemakers (Evia, Entovis, Estella, Ecuro, Effecta), electrodes (Solia, Safio S, Siello, Setrox, Selos)
- Tachycardia therapy: Defibrillators (Lumax 3 Family, Lumax 5 Family, Lumax 6 Family, Lumax 7 Family, Lumax VR-T DX), electrodes (Linox smart)
- Electrophysiology: ablation catheters (AlCath Gold, AlCath Flux, AlCath Flux Gold, AlCath Flux eXtra Gold von VascoMed, Trignum Flux Gold), steerable diagnostic catheters (Lexx, ViaCath), non-steerable diagnostic catheters (MultiCath von VascoMed, Woxx)
- Cardiac resynchronization: CRT devices (Lumax 3 Family, Lumax 5 Family, Lumax 7 Family, Evia HF-T, Entovis HF-T), electrodes (Corox OTW, Sentus OTW UP), lead systems and accessories (Selectra, ScoutPro, ScoutPro IC)
- Coronary vascular intervention: coronary Sirolimus-eluting stent system Orsiro, balloon-expanding cobalt chromium coronary stent system PRO-Kinetic Energy, coronary Paclitaxel-eluting balloon catheter Pantera Lux, coronary balloon catheters (Pantera, Pantera LEO, AngioSclupt PTCA), coronary leads (Streamer, Cruiser, Galeo Pro), drug-eluting absorbable metal scaffold with magnesium (DREAMS)
- Peripheral vascular intervention: peripheral balloon-expanding stent systems (Dynamic, Dynamic Renal, PRO-Kinetic Energy Explorer), peripheral self-expanding stent systems (Astron, Astron Pulsar, Pulsar-18), peripheral balloon catheters (Passeo-14, Passeo-18. Passeo-35, AngioSculpt PTA, Elect Explorer), peripheral leads (Cruiser, Cruiser-18, XT-14), introducer sheath (Fortress)
- Implantable heart monitor for the continuous monitoring of patients with atrial flutter or undiagnosed syncopes (BioMonitor)
- External devices: ICS 3000, Reliaty, Renamic, Qiona ablation pump, heart stimulator UHS 3000
- Patient devices: Cardio Messenger
- "BIOTRONIK SE & Co. KG". Company profiles. Hoovers. Retrieved 3 April 2011.