Bismuth subgallate

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Bismuth subgallate
Bismuth subgallate.svg
Systematic (IUPAC) name
2,7-dihydroxy-1,3,2-benzodioxabismole-5-carboxylic acid
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
Identifiers
CAS number 99-26-3 N
ATC code A07BB
PubChem CID 16682999
ChemSpider 10607905 YesY
UNII YIW503MI7V N
ChEBI CHEBI:31292 YesY
Chemical data
Formula C7H5BiO6 
Mol. mass 394.091 g·mol−1
Physical data
Density 1.1 g/cm³
 N (what is this?)  (verify)

Bismuth subgallate, with a chemical formula C7H5BiO6, is commonly used to treat malodor by deodorizing flatulence and stools. In the United States it is the active ingredient in Devrom (internal deodorant), an over-the-counter FDA-approved medicine. Also, it has been used to treat Helicobacter pylori infection and is used in wound therapy. As an internal deodorant, it is commonly used by individuals who have had ostomy surgery, bariatric surgery, fecal incontinence, and irritable bowel syndrome.[1]

It can cause darkening of the tongue and stools, which is temporary and harmless. In 1974, a reversible encephalopathy was noted and examined in four colon cancer patients taking bismuth subgallate after abdominoperineal resection.[2]

Also, a double blind study in 1974 reported its effectiveness as a flatulence/stool deodorant in ileostomy patients.[3]

Safety[edit]

It is classified as nontoxic.[by whom?]

See also[edit]

External links[edit]

  • American Cancer Society: Ileostomy Guide [1]
  • Cleveland Clinic-Having an Ileostomy– A Primer for New Ostomates [2]
  • United Ostomy Association of America-Ileostomy Guide [3]
  • The Ostomy Files:The Issue of Oral Medications and a Fecal Ostomy [4]
  • Devrom website [5]
  • Gulp: Adventures on the Alimentary Canal by Mary Roach [6]

References[edit]

  1. ^ Gorbach S. L. (1990). "Bismuth therapy in gastrointestinal diseases". Gastroenterology 99 (3): 863–75. PMID 2199292. 
  2. ^ Burns R., Thomas D. W., Barron V. J. (1974). "Reversible encephalopathy possibly associated with bismuth subgallate ingestion". British Medical Journal 9 (1): 220–3. PMC 1633100. PMID 4818163. 
  3. ^ Sparberg M. (1974). "Correspondence: Bismuth subgallate as an effective means for the control of ileostomy odor: a double blind study". Gastroenterology 66 (3): 476. PMID 4813513.