Degmacyte

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A degmacyte (aka "bite cell") is an abnormally shaped red blood cell with one or more semicircular portions removed from the cell margin.[1] These "bites" result from the removal of denatured hemoglobin by macrophages in the spleen.[2] Glucose-6-phosphate dehydrogenase deficiency, in which uncontrolled oxidative stress causes hemoglobin to denature and form Heinz bodies, is a common disorder that leads to the formation of bite cells.

The "bites" in degmacytes are smaller than the missing red blood cell fragments seen in schistocytes.

References[edit]

  1. ^ Yoo, D; Lessin, LS (1992). "Drug-associated 'bite cell' Hemolytic anemia". The American Journal of Medicine 92 (3): 243–8. doi:10.1016/0002-9343(92)90071-I. PMID 1546722. 
  2. ^ http://www.mclno.org/webresources/kbase/cellatlas/Bite%20Cell.html