Bitot's spots

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Bitot's spots
Classification and external resources
ICD-10 E50.1
ICD-9 264.1

Bitot's spots are the buildup of keratin located superficially in the conjunctiva, which are oval, triangular or irregular in shape. These spots are a sign of vitamin A deficiency and are associated with conjunctival xerosis. In 1863, Pierre Bitot (1822-1888), a French physician, first described these spots.[1]

In ancient Egypt, this was treated with animal liver, which is where vitamin A is stored[citation needed].


  1. Vitamin A
  2. Beta carotene


  1. ^ Shukla, M. and Behari, K. (1979), Congenital Bitot spots, Indian Journal of Ophthalmology, 27(2), 63-64

External links[edit]