It was the band's final release on Elektra Records. This was the first album not to feature the vocals of David Wayne, due to his departure to form the band Reverend. This release featured new vocalist Mike Howe (ex-Heretic) and guitarist John Marshall, who took over Kurdt Vanderhoof's position. Kurdt Vanderhoof had produced Heretic's final album Breaking Point previously. It seems that is how Mike Howe came to the attention of Metal Church. Ironically, David Wayne's new project was made up of the remaining members of Heretic.
Former Flotsam and Jetsam bassist Michael Spencer has stated that Blessing in Disguise was supposed to be the title of the band's second album before settling with its current name No Place for Disgrace. After Spencer left Flotsam and Jetsam, Michael Alago (the A&R of Elektra) let Metal Church use Blessing in Disguise as the name of their third album, which was released nine months after No Place for Disgrace.
Reviews for Blessing in Disguise have been mostly positive. Allmusic's Jason Anderson awards the album four stars out of five, and states: "Perhaps the finest Metal Church release, Blessing in Disguise offers some of the best material in the group's long career."
Blessing in Disguise entered the Billboard 200 chart on April 8, 1989, two months after its release. The album itself peaked at number 75 (the band's highest chart position to date) and remained on the chart for 15 weeks.