Blood–ocular barrier

From Wikipedia, the free encyclopedia
Jump to: navigation, search

The blood-ocular barrier is a barrier created by endothelium of capillaries of the retina and iris, ciliary epithelium and retinal pigment epithelium.[1] It is a physical barrier between the local blood vessels and most parts of the eye itself, and stops many substances including drugs from traveling across it.[2] Inflammation can break down this barrier allowing drugs and large molecules to penetrate into the eye.[3] As the inflammation subsides, this barrier usually returns.

It consists of the following components:

See also[edit]

References[edit]

  1. ^ Peiffer, Robert L.; Petersen-Jones, Simon M. (2001). Small animal ophthalmology: a problem-oriented approach. Elsevier Health Sciences. p. 46. ISBN 978-0-7020-2570-9. 
  2. ^ a b Kramer, Axel; Behrens-Baumann, Wolfgang (2002). Antiseptic prophylaxis and therapy in ocular infections: principles, clinical practice, and infection control. Karger Publishers. p. 72. ISBN 978-3-8055-7316-0. 
  3. ^ Giguère, Steeve; Prescott, John F.; Desmond Baggot, J. (2006). Antimicrobial therapy in veterinary medicine. Wiley-Blackwell. p. 366. ISBN 978-0-8138-0656-3. 
  4. ^ Coscas, G.; Cunha-Vaz, J.; Loewenstein, A.; Soubrane (2010). Macular Edema: A Practical Approach. Karger Publishers. p. 59. ISBN 978-3-8055-9434-9. 
  5. ^ J. Maggs, David; E. Miller, Paul; Ofri; H. Slatter, Douglas (2008). Slatter's fundamentals of veterinary ophthalmology. Elsevier Health Sciences. p. 455. ISBN 978-0-7216-0561-6.