Boluspor became a professional club when they entered the TFF Second League during the 1966-67 season. They were first promoted into the TFF First League after the 1969-70 season. They were promoted to the Süper Lig in 1972-73 and finished third, their highest finish in the Süper Lig, the following season.
The club has competed in continental competition once, losing to Dinamo Bucharest, in the 1974-75 UEFA Cup. They also competed in the now defunct Balkans Cup, winning matches against clubs such as Sofya Akademik and Sport Clup Bacau, but never won the cup.