Bouveault–Blanc reduction

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The Bouveault–Blanc reduction is a chemical reaction in which an ester is reduced to primary alcohols using absolute ethanol and sodium metal.[1][2][3]

The Bouveault-Blanc reduction

This reaction is an inexpensive and large-scale alternative to lithium aluminium hydride reduction of esters.

Reaction mechanism[edit]

Sodium metal is a single-electron reducing agent, meaning the sodium metal will transfer electrons one at a time. Four sodium atoms are required to fully reduce each ester to alcohols. Ethanol serves as a proton source.

The mechanism of the Bouveault-Blanc reduction

See also[edit]


  1. ^ Bouveault, L.; Blanc, G. (1903). Compt. Rend. 136: 1676.  Missing or empty |title= (help)
  2. ^ Bouveault, L.; Blanc, G. (1904). Bull. Soc. Chim. France 31: 666.  Missing or empty |title= (help)
  3. ^ Adkins, H.; Gillespie, R. H. (1955). "Oleyl alcohol". Org. Synth. ; Coll. Vol. 3, p. 671 

External links[edit]