Brevican

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Brevican
Identifiers
Symbols BCAN ; BEHAB; CSPG7
External IDs OMIM600347 MGI1096385 HomoloGene7244 GeneCards: BCAN Gene
RNA expression pattern
PBB GE BCAN 91920 at tn.png
PBB GE BCAN 219107 at tn.png
PBB GE BCAN 221623 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 63827 12032
Ensembl ENSG00000132692 ENSMUSG00000004892
UniProt Q96GW7 Q61361
RefSeq (mRNA) NM_021948 NM_001109758
RefSeq (protein) NP_068767 NP_001103228
Location (UCSC) Chr 1:
156.61 – 156.63 Mb
Chr 3:
87.99 – 88 Mb
PubMed search [1] [2]

Brevican core protein is a protein that in humans is encoded by the BCAN gene.[1][2][3] Brevican is a member of the lectican protein family.

In melanocytic cells BCAN gene expression may be regulated by MITF.[4]

References[edit]

  1. ^ Gary SC, Zerillo CA, Chiang VL, Gaw JU, Gray G, Hockfield S (Dec 2000). "cDNA cloning, chromosomal localization, and expression analysis of human BEHAB/brevican, a brain specific proteoglycan regulated during cortical development and in glioma". Gene 256 (1-2): 139–47. doi:10.1016/S0378-1119(00)00362-0. PMID 11054543. 
  2. ^ Nomoto H, Oohashi T, Hirakawa S, Ueki Y, Ohtsuki H, Ninomiya Y (Mar 2002). "Human BRAL1 and BCAN genes that belong to the link-module superfamily are tandemly arranged on chromosome 1q21-23". Acta Med Okayama 56 (1): 25–9. PMID 11873941. 
  3. ^ "Entrez Gene: BCAN brevican". 
  4. ^ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971. 

Further reading[edit]