Brill–Zinsser disease

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Bril–Zinser disease
Classification and external resources
ICD-10 A75.1
DiseasesDB 32208

Bril–Zinser disease is a delayed relapse of epidemic typhus, caused by Ricketttsia prowazekii. After a patient contracts epidemic typhus from the fecal matter of an infected louse (Pediculus humanus), the rickettsia can remain latent and reactivate months or years later, with symptoms similar to or even identical to the original attack of typhus, including a maculopapular rash.[1] This reactivation event can then be transmitted to other individuals through fecal matter of the louse vector, and form the focus for a new epidemic of typhus.

See also[edit]


  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1130. ISBN 1-4160-2999-0.