Perrineau is perhaps best known for her recurring appearance on US TV show Lost, appearing in the Season 1 episodes of "Outlaws", as the girlfriend of Sawyer, and in the episode "Numbers", as the woman who read the lottery numbers. Her acting credits also include the role of Dara in the romantic-comedy Saving Face, as well as appearing in the upcoming movie Your Name Here, currently in post-production.
Brittany is the wife of actor Harold Perrineau. The couple has three daughters, Aurora, born 1994, and Wynter Aria, born on May 7, 2008. In September 2012, the couple announced they were expecting their third child in late winter. On March 21, 2013, Brittany gave birth to a third daughter, named Holiday Grace